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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
17.27
Human Site:
T839
Identified Species:
31.67
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
T839
S
K
M
P
A
V
G
T
E
D
R
P
L
G
K
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S819
S
K
K
S
A
N
G
S
D
D
K
A
S
C
K
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
T839
S
K
I
P
T
V
G
T
E
D
R
P
L
G
K
Dog
Lupus familis
XP_534693
2280
250152
A908
S
K
M
P
A
V
G
A
E
D
R
P
L
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
T834
S
K
M
P
T
V
G
T
E
E
R
P
P
G
K
Rat
Rattus norvegicus
NP_001101807
1374
149708
S45
L
E
Q
H
P
A
F
S
P
V
M
N
Y
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
G801
G
S
K
K
I
L
S
G
T
D
D
K
S
N
C
Chicken
Gallus gallus
XP_415317
2195
241321
S816
S
K
M
P
A
V
G
S
E
E
R
P
V
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
P754
S
G
G
S
K
P
L
P
T
T
S
L
I
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
D1034
A
G
N
I
Q
A
E
D
L
T
K
M
F
P
T
Honey Bee
Apis mellifera
XP_393643
1982
216109
S653
R
R
Q
R
D
D
P
S
K
P
G
S
L
F
T
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
K1189
L
A
Q
K
V
V
D
K
R
P
S
Q
F
A
I
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
40
86.6
93.3
N.A.
80
0
N.A.
6.6
80
N.A.
6.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
60
93.3
93.3
N.A.
86.6
13.3
N.A.
13.3
100
N.A.
20
N.A.
13.3
26.6
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
31
16
0
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
0
8
8
8
8
8
39
8
0
0
0
8
% D
% Glu:
0
8
0
0
0
0
8
0
39
16
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
16
8
0
% F
% Gly:
8
16
8
0
0
0
47
8
0
0
8
0
0
39
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
8
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
47
16
16
8
0
0
8
8
0
16
8
0
8
47
% K
% Leu:
16
0
0
0
0
8
8
0
8
0
0
8
31
0
0
% L
% Met:
0
0
31
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
39
8
8
8
8
8
16
0
39
8
8
0
% P
% Gln:
0
0
24
0
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
8
0
8
0
0
0
0
8
0
39
0
0
0
0
% R
% Ser:
54
8
0
16
0
0
8
31
0
0
16
8
16
0
0
% S
% Thr:
0
0
0
0
16
0
0
24
16
16
0
0
0
0
16
% T
% Val:
0
0
0
0
8
47
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _